The remedy of epithelial lesions has been a crucial subject of different studies. Natural herbal products play a vital role as compatible therapeutic sources. Aloe Vera gel has powerful effects on wounds, specifically cutaneous abrasion healing. In current study, we examined the effect of Aloe Vera gel on dermal wound allay and found out that Aloe Vera improves the wound healing by reducing the cutaneous inflammation. As additional effect, it is also useful in hair growth. This research was conducted in Albino Rats. Mycitracin in the form of ointment was applied for evaluating the lesion allay ability in the incision wound model as comparative medicine. The results illustrated the lesion contraction as well as reduction in the inflammation which firmly supports the healing properties of Aloe Vera.