PHYTOCHEMICAL INVESTIGATION AND PHARMACOLOGICAL EVALUATION OF ERYTHRAEARAMOSISSIMA

G. Rahman, R. A. Khan

G. Rahman and *R. A. Khan
Department of Biotechnology, University of Science and Technology, Bannu, KPK, Pakistan

Corresponding Author: rahmatgul_81@yahoo.com
Page Number(s): 1730-1733
Published Online First: October 01, 2017
Publication Date: October 01, 2017

ABSTRACT

Erythraea ramosissimais traditionally used for the treatment of various human diseases. In the present study was aimed at the in-vitro pharmacological and phytochemical analysis of the methanol extract of Erythraea ramosissima. The sample extract of Erythraea ramosissima showed potent antioxidant activities (98.1±5.2%) inhibition of DPPH, Hydrogen peroxide scavenging activity was (95.1±8.4%), total antioxidant activity was 92.1±5.4 and ABTS scavenging activity of the extract was 94.1±5.4 at 3000µg/ml.Qualitative analysis reveals the presence of saponins, tannins, anthraquinons, alkaloids, coumarins and flavonoids.I the cytotoxicity assay, at 3000μg/mlconcentrations maximum death of brine shrimp was reported. In the light of the present result it is inferred that methanolic extract of Erythraea ramosissima can be used as a free radicle scavenger and as an anticancer agent.

Keywords: Erythraea ramosissima, scavenging activity DPPH, ABTS, phenolics, flavonoid compounds, cytotoxicity
Open Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( https://creativecommons.org/licenses/by/4.0/).


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