Article Abstract

Full Text
Volume 35, No. (1), 2025 (February)
MAJOR COMPONENT AND ANTIMICROBIAL ACTIVITY OF THE EXTRACT OF BITTER LEAF (Vernonia amydalina) AGAINST Vibrio parahaemolyticus
Van Nhan Le, Quang Minh Bui, Viet Anh Le, Van Diep Le, Thi Thanh Mai Nguyen, Hung Manh Nguyen, Cong Thuong Phi, Van Tien Tran, Thi Quynh Bui, Hai Anh Tran, Thi Oanh Doan, Nguyen Khang La

V. N. Le¹*, Q. M. Bui², V. A. Le³, V. D. Le⁴, T. T. M. Nguyen⁵, H. M. Nguyen⁶, C. T. Phi⁷, V. T. Tran⁸, T. Q. Bui⁹, H. A. Tran¹⁰, T. O. Doan¹¹, N. K. La¹²

¹ Center for High Technology Research and Development, Vietnam Academy of Science and Technology, Hanoi 10072, Vietnam,
² Center for High Technology Research and Development, Vietnam Academy of Science and Technology, Hanoi 10072, Vietnam,
³ Center for High Technology Research and Development, Vietnam Academy of Science and Technology, Hanoi 10072, Vietnam,
⁴ Cyber School,Vinh University, Nghe An 43105, Vietnam,
⁵ Institute of Agriculture and Natural Resources, Vinh University, Nghe An 43105, Vietnam,
⁶ Institute of Ecology and Biological Resources, Vietnam Academy of Science and Technology, Hanoi 10072, Vietnam,
⁷ Ministry of Science and Technology, Hanoi 10055, Vietnam,
⁸ National Academy of Public Administration, Hanoi 11550, Vietnam,
⁹ Center for High Technology Research and Development, Vietnam Academy of Science and Technology, Hanoi 10072, Vietnam,
¹⁰ Center for High Technology Research and Development, Vietnam Academy of Science and Technology, Hanoi 10072, Vietnam,
¹¹ Hanoi University of Natural Resources and Environment, Faculty of Environment, Hanoi 11906, Viet Nam,
¹² Institute for Forest Ecology and Environment, Vietnam National University of Foresty, Hanoi 13417, Vietnam,

Corresponding Author: levannhan.na@gmail.com
DOI: https://doi.org/10.36899/JAPS.2025.1.0004
Page Number(s): 58-67
Published Online First: December 21, 2024
Publication Date: February 18, 2025
ABSTRACT

It is an undeniable fact that natural bioactive compounds extracted from diverse plants and herbs have attracted significant public attention and scientific interest due to their health-promoting benefits as antioxidants and antimicrobial agents. In this research, the main phytochemical compositions of V. amygdalina leaves were determined by Gas chromatography–mass spectometry (GC-MS). There were 18 groups detected from the methanol extract of V. amygdalina leaves, in which, fatty acids were the major component (55.29%), followed by the ketone group at 10.44%. Phenol and terpenoid compounds comprised 6.19% and 5.13% respectively, ranking third and fourth in abundance. The antibacterial properties of the extract from V. amygdalina leaves were evaluated against V. parahaemolyticus which caused Acute hepatopancreatic necrosis disease (AHPND) in Whiteleg shrimp (Liptopenaeus vannamei). The antibacterial zone diameters of the leaf extract ranged from 9.5 mm to 19.0 mm during 72 hours of the inhibition, corresponding to the concentration of V. amygdalina changed from 200 mg.mL-1 to 500 mg.mL-1. This illustrates the potential application of V. amygdalina leaf extracts as the supply food or used to produce bio-preparations for preventing and controlling the growth of V. parahaemolyticus in shrimp culture industry.
Keywords: Vernonia amygdalina, Vibrio parahaemolyticus, AHPND, Liptopenaeus vannamei, antimicrobial activity

Indexing

Web of Science (SCIE)

SCOPUS (Q3)

Status

Journal Metrics

Journal Impact Factor: 0.5 | (JCR Year: 2025) | Cite Score: 1.3

HEC Category: W

Current

ISSN Details

Print ISSN: 1018-7081

Electronic ISSN: 2309-8694

Verified
Search the Journal

Use the fields below to search for articles by Title, Author, or Keywords.

© , Developed by HISOFT