Zoonotic infectious diseases like Zika, Ebola, Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory
Syndrome (MERS) and the very recent Coronavirus Disease (COVID-19) can leap from one species to another and
within the same species by constantly mutating to defy therapeutics and vaccines. The SARS-CoV-2 is emerging to be
closely related to bat coronaviruses, highlighting the need of One Health approach to combat new disease threats that
affects both animals and human beings. One Health is a collaborative, multi-sectoral and trans-disciplinary approach -
working at the local, regional, national, and global levels, with the goal of achieving optimal health outcomes
recognizing the interconnection between people, animals, plants and their shared environment. Therefore, One Health
can be considered as a global approach to maintain health of human beings, animals and ecosystem. The present study
plots the One Health publications available in Web of Science (WoS) database from 1997 to 2021. WoS provides access
to databases that supplies reference and citation data from research publications. Globally, a total of 4397 publications
were published. In Indian context, about 230 scientific literatures were published and only 94 publications were found
relevant to policy makers. Relevance to policy-makers was judged by the presence of policy implications in the research
publication. Further, data were analysed using bibliometrix R-package to evaluate research publications of authors, the
annual growth of research publications and citation analysis to understand the status of One Health research in India. The
annual growth rate of publications in India was 47.48 per cent with collaboration index 6.58, which is greater than global
collaboration index. Three-fields plot exhibited that in Guru Angad Dev Veterinary and Animal Science University
(GADVASU), Ludhiana, dedicated research on One Health is being carried out with 13 publications on One Health. The
collaboration network analysis found that Indian authors are highly collaborative with researchers from Australia, USA
and Germany. In addition to these formal collaborations, there is opportunity to strengthen informal collaboration
through digital platforms like Google Scholar, ResearchGate, LinkedIn, Facebook, Google+, Twitter etc. With judicious
use, they could be used to sprout fruitful collaborations. Thus, the trend of policy oriented One Health research in India
was analysed to illuminate on the possible researchable themes and future line of works.