RT Journal T1 CHARACTERIZING SILVER NANOPARTICLES BIOSYNTHESIZED FROM SALVIA ROSMARINUS AND ASSESSING THEIR IN VITRO ANTIFUNGAL AND CYTOTOXIC ACTIVITIES AGAINST PHYTOPATHOGENS AND CERVICAL CELLS A1 H. Rizwana A1 N. A. Bokahri A1 S. A. Rashed A1 S. A. Shehri A1 M. A. Awad A1 N. Merghani A1 H. Tabasuum JF Journal of Animal and Plant Sciences JO JAPS SN 1018-7081 VO 32 IS 3 SP 764 OP 774 YR 2022 FD 2022/05/30 DO DOI http://doi.org/10.36899/JAPS.2022.3.0478 AB

Nanotechnology is significantly revolutionizing world agriculture through engineered nanomaterials, which contribute to enhancing agricultural production by controlling fungal and bacterial phytopathogens and, consequently, minimizing crop losses. In this study green silver nanoparticles (AgNPs) were biosynthesized using aqueous extracts of organically grown Salvia rosmarinus leaves.The AgNPs were examined and characterized with ultraviolet–visible spectroscopy, dynamic light scattering, energy-dispersive X-ray spectroscopy, transmission electron microscopy, and Fourier transform infrared spectroscopy. Their antifungal activity was evaluated against an array of fungal phytopathogens. In addition, the AgNPs were tested for their cytotoxic properties using microculture tetrazolium assays against the cervical cancer HeLa cell line. The nanoparticle size ranged between 7 and 58 nm, and the AgNPs significantly inhibited Fusarium oxysporum (61%), followed by Alternaria alternata (50%). The in vitro cytotoxicity assay against HeLa cells showed potent inhibition with a median inhibitory concentration of 11.28 ± 0.33 µg/mL. S. rosmarinus biosynthesized AgNPs demonstrate significant antifungal and antiproliferative activities against plant pathogens and HeLa cells.

K1 Salvia rosmarinus, silver nanoparticles (AgNPs), phytopathogens, cytotoxicity PB Pakistan Agricultural Scientists Forum LK https://thejaps.org.pk/AbstractView.aspx?mid=Biot-20-0021