RT Journal
T1 STUDY ON ROLE OF KISSPEPTIN IN REPRODUCTIVE DEVELOPMENT AND INTER-RELATIONSHIP WITH ENDOCRINE MARKERS FOR NILI-RAVI BUFFALO BULLS (BUBALUS BUBALIS)
A1 M. K. Shahzad
A1 K. A. Majeed
A1 M. S. Yousaf
A1 S. M. H. Andrabi
A1 I. Rabbani
A1 M. A. Rashid
A1 S. K. Tahir
A1 D. H. Mughal
A1 H. Zaneb
A1 S. Abbas
A1 H. Rehman
JF Journal of Animal and Plant Sciences
JO JAPS
SN 1018-7081
VO 32
IS 2
SP 345
OP 352
YR 2022
FD 2022/03/15
DO DOI https://doi.org/10.36899/JAPS.2022.2.0431
AB <p>Kisspeptin, a neuropeptide, is known to be a regulator of the hypothalamic-pituitary-gonadal axis and is considered to have a role in the onset of puberty. The objective of the present study was to investigate the potential role of kisspeptin and its correlation with anthropometric parameters, testicular biometry, serum profiles of reproductive as well as selected metabolic hormones in prepubertal and postpubertal Nili-Ravi buffalo bulls (<em>Bubalus bubalis</em>). Anthropometric parameters and testicular biometry were measured, and blood samples were collected from prepubertal (n = 20) and postpubertal (n = 20) buffalo bulls during slaughtering. Serum samples were analysed for the assessment of circulating levels of kisspeptin, gonadotropin-releasing hormone (GnRH), follicle-stimulating hormone (FSH), luteinizing hormone (LH), testosterone, triiodothyronine (T3), thyroxin (T4), and insulin-like growth factor (IGF-1). Results demonstrated that there was a non-significant change in serum concentration of kisspeptin between prepubertal and postpubertal animals. However, concentrations of GnRH (P &lt; 0.001), FSH (P &lt; 0.05), T3 (P &lt; 0.01) and most of the anthropometric parameters were higher in the postpubertal calves than the prepubertal calves. Correlation analysis revealed that LH had significant correlation (P &lt; 0.05) with testicular developmental parameters and IGF (P &lt; 0.01) in postpubertal calves. Kisspeptin showed positive correlations (P &lt; 0.05) with the width of the chest and width of the pelvis in prepubertal and postpubertal calves respectively. The IGF, testosterone, and T3 also have shown associations with some of the anthropometric parameters showing their roles in the pubertal development of calves. In conclusion, the circulating level of kisspeptin did not influence either reproductive or selected metabolic hormones suggesting that there are some other unknown mechanism(s) that influence the reproductive developments of buffalo bulls which need to be addressed in further studies.</p>
K1 Anthropometric parameters, Bubalus bubalis, hormones, kisspeptin, puberty
PB Pakistan Agricultural Scientists Forum
LK https://thejaps.org.pk/AbstractView.aspx?mid=AS-20-0107