RT Journal T1 SEROLOGICAL AND MOLECULAR INVESTIGATION OF ZOONOTIC POTENTIAL OF HEPATITIS E VIRUS AMONG FARM ANIMALS IN TURKIYE A1 Caglar OKULMUS A1 Abdurrahman Anil CAGIRGAN A1 Yakup YILDIRIM A1 Ozge Sevinc KORKMAZ AKAR A1 Ali KUCUK JF Journal of Animal and Plant Sciences JO JAPS SN 1018-7081 VO 35 IS 4 SP 1068 OP 1075 YR 2025 FD 2025/07/29 DO DOI https://doi.org/10.36899/JAPS.2025.4.0091 AB

The Orthohepevirus A strain of hepatitis E virus (HEV) is one of the world's leading zoonotic viruses and poses significant public health concerns. HEV susceptibility has been demonstrated in a wide range of animal species and have the capacity to transmit the virus to humans. However, the contribution of Orthohepevirus A serotypes to HEV epidemiology remains poorly understood. Blood serum samples were collected from 188 domestic animals from different farms selected by random sampling in Burdur province of Türkiye. The animal group consisted of 22 horses, 22 donkeys, 30 sheep, 25 goats, 27 cattle, 35 cats and 27 dogs. An overall HEV seroprevalence of 4.79% was observed. The presence of HEV antibodies in goats, horses, and donkeys was detected for the first time in Türkiye. Statistical tests performed to determine the difference between seropositivity rates according to animal species were found significant at p ≤ 0.05. Orthohepevirus A RNA was undetectable in all samples using gel-based nested RT-PCR. In this first report on HEV in farm animals in Türkiye, the presence of HEV antibodies suggests that farm animals may have an important role in spreading infection.

K1 Domestic animals, Hepatitis E virus, HEV antibodies, Türkiye, Zoonotic potential PB Pakistan Agricultural Scientists Forum LK https://thejaps.org.pk/AbstractView.aspx?mid=2025-JAPS-7