RT Journal T1 COMPARATIVE STUDIES ON SEDATIVE AND ANALGESIC EFFECTS OF XYLAZINE AND DETOMIDINE IN GOATS A1 Shah A1 Z. A1 A. B. Kalhore A1 A. B. Kachiwal A1 I. Ahmad A1 H A1 Sattar A1 M. A. Khan A1 Z. U. Rehman A1 F. A. Khan A1 T. Hussain A1 H. A. Ullah JF Journal of Animal and Plant Sciences JO JAPS SN 1018-7081 VO 23 IS 1 SP 39 OP 42 YR 2013 FD 2013/02/01 DO DOI NA AB

An experiment was carried out to compare the sedative and analgesic effects of intravenous administration of xylazine (0.1mg/kg) and detomidine (50μg/kg), in six healthy goats (Bari breed). Onset of sedation occurred within 29 ± 3.74 and 55.66 ± 5.57 seconds which lasted for 77.59 ± 4.38, and 85.38 ± 2.76 minutes with xylazine and detomidine, respectively. Skin analgesia occurred within 5.66 ± 3.26, and 12. 83 ± 3.48 minutes and the mean values for duration of analgesia were 40.66 ± 3.32 and 33.5 ± 3.67 minutes after administrations of xylazine and detomidine, respectively. Moderate to deep degree of analgesia was achieved by the administration of xylazine and detomidine. Some side effects like salivation, frequent urination, defecation, tympany, protrusion of the tongue, head drooping and bellowing were observed after administration of xylazine and detomidine. It is concluded that these alpha-2 adrenergic agonists are safe to be used in goats.

K1 Sedation, goat, analgesia, detomidine, xylazine PB Pakistan Agricultural Scientists Forum LK https://thejaps.org.pk/AbstractView.aspx?mid=2013-JAPS-1010