RT Journal
T1 ANTIBACTERIAL ACTIVITY OF A TRYPSIN-CHYMOTRYPSIN-ELASTASE INHIBITOR ISOLATED FROM LAVATERA CASHMERIANA CAMB.SEEDS
A1 S. Rakashanda
A1 M. Ishaq
A1 A. Masood
A1 S. Amin
JF Journal of Animal and Plant Sciences
JO JAPS
SN 1018-7081
VO 22
IS 4
SP 983
OP 986
YR 2012
FD 2012/08/01
DO DOI NA
AB <p>Protease inhibitors were extracted from the seeds of&nbsp;<em>Lavatera cashmeriana</em>&nbsp;Cambby ammonium sulphate precipitation and purified by chromatography on DEAE-cellulose and Sephadex G-100 column. The bound protein eluted into four major peaks which we named as LC-pi I, II, III and IV, all showing strong anti protease activity against trypsin, chymotrypsin and elastase. LC-pi I was screened for antibacterial activity against&nbsp;<em>Klebsiella pnuemoniae, &nbsp;Escherichia coli</em>&nbsp;and&nbsp;<em>Pseudomonas aeruginosa</em>. The protease inhibitor showed strong antibacterial activity against&nbsp;<em>Klebsiella pnuemoniae &nbsp;</em>and&nbsp;<em>Pseudomonas aeruginosa</em>&nbsp;but was less active against&nbsp;<em>&nbsp;Escherichia&nbsp; coli</em>.</p>
K1 Lavatera cashmeriana Camb, antibacterial activity, LC-pi I, nutrient agar.
PB Pakistan Agricultural Scientists Forum
LK https://thejaps.org.pk/AbstractView.aspx?mid=2012-JAPS-427