RT Journal T1 IMMUNE RESPONSE AND TICK REJECTION PATTERN OF MIDGUT AND SALIVARY GLAND VACCINES AGAINST LOCALLY PREVALENT BOOPHILUS MICROPLUS TICKS A1 M. Asif A1 K. Saeed A1 K. Muhammad JF Journal of Animal and Plant Sciences JO JAPS SN 1018-7081 VO 21 IS 1 SP 12 OP 15 YR 2011 FD 2011/02/01 DO DOI NA AB

Midguts and salivary glands were isolated from partially engorged female ticks and processed for a vaccine candidate. The protein contents were measured and two different oil-based vaccines were prepared; midgut vaccine (MGV) and salivary gland vaccine (SGV). These vaccines were administered sub-cutaneously on days 0, 14 and 21. Their efficacy was monitored on the basis of antibody titers as determined by agar gel precipitation test. Ticks rejection on immunized hosts was evaluated in terms of attachment, mortality, oviposition, and hatchability of eggs. MGV offered significantly better control of B. microplus as compared to SGV. The highest antibody titers were observed in animals given MGV with a GMT of 5.5 which was 45.3% higher than animals given SGV.

K1 Immunization, Boophilus microplus, rabbits, midgut, salivary glands PB Pakistan Agricultural Scientists Forum LK https://thejaps.org.pk/AbstractView.aspx?mid=2011-JAPS-110