PHYTOCHEMICAL INVESTIGATION AND PHARMACOLOGICAL EVALUATION OF ERYTHRAEARAMOSISSIMA Authors: G. Rahman, R. A. Khan Journal: Journal of Animal and Plant Sciences (JAPS) ISSN: 1018-7081 (Print), 2309-8694 (Online) Volume: 27 Issue: 5 Pages: 1730-1733 Year: 2017 DOI: NA URL: https://doi.org/NA Publisher: Pakistan Agricultural Scientists Forum Abstract:

Erythraea ramosissimais traditionally used for the treatment of various human diseases. In the present study was aimed at the in-vitro pharmacological and phytochemical analysis of the methanol extract of Erythraea ramosissima. The sample extract of Erythraea ramosissima showed potent antioxidant activities (98.1±5.2%) inhibition of DPPH, Hydrogen peroxide scavenging activity was (95.1±8.4%), total antioxidant activity was 92.1±5.4 and ABTS scavenging activity of the extract was 94.1±5.4 at 3000µg/ml.Qualitative analysis reveals the presence of saponins, tannins, anthraquinons, alkaloids, coumarins and flavonoids.I the cytotoxicity assay, at 3000μg/mlconcentrations maximum death of brine shrimp was reported. In the light of the present result it is inferred that methanolic extract of Erythraea ramosissima can be used as a free radicle scavenger and as an anticancer agent.

Keywords: Erythraea ramosissima, scavenging activity DPPH, ABTS, phenolics, flavonoid compounds, cytotoxicity