17 Hafeez. M.A A. Sattar K. Ashraf M. Mehdi A. Rafique M.S. Mahmood F. Aslam I. Hussain M.R. Zia Journal of Animal and Plant Sciences JAPS 20202020/03/25 30 3 627-633 1018-7081 https://doi.org/10.36899/JAPS.2020.3.0074 <p>The aim of study was to determine the effect of (Brufen^TM) alone and in conjugation with vitamin E and Selenium in broilers against coccidiosis. One hundred randomly allocated (25 birds in each group&nbsp;<em>i.e.</em>, A, B, C &amp; D) day-old broiler chicks underwent the current trial. Group A, B and C were challenged with 60,000-70,000 sporulated oocysts of genus&nbsp;<em>Eimeria&nbsp;</em>at 21^st&nbsp;day of age. Group A and B were administered with (Brufen^TM) and combination of (Brufen^TM) with vitamin E and Selenium (E-Sel^TM) @ 100mg/kg body weight and 1ml/10 liters of drinking water, respectively. Group C and D were kept as negative (infected &amp; un-medicated) and positive (un-infected &amp; un-medicated) controls, respectively. Therapeutic response was measured on the basis of mortality, oocysts count, weight gains, coccidial lesion scorings and weight of lymphoid organs. Maximum mortality was observed in group C (17/25), followed by group A (12/25), than in group B (8/25) post coccidial infection. Coccidial lesion scores and oocysts count were significantly lower in groups (A &amp; B) administered with Ibuprofen. Moreover, maximum weight gain and reduced lymphoid organ to body weight ratio were also observed in chicken of group B as compared to A, C and D. The study suggested synergistic and enhanced protective response of Ibuprofen in combination with vitamin E and Selenium against chicken coccidiosis.</p> coccidiosis, ibuprofen, vitamin E and selenium, broilers Pakistan Agricultural Scientists Forum https://thejaps.org.pk/AbstractView.aspx?mid=VS-17-0087