17 S. Zhao G. R. Mustafa S. Yang W. Deng X. Yu L. Zou＊ Journal of Animal and Plant Sciences JAPS 20202020/11/09 31 3 923-928 1018-7081 https://doi.org/10.36899/JAPS.2021.3.0283 <p><em>Escherichia coli</em>&nbsp;is normal gut commensal for animals as well as humans, meanwhile it can be present in the environment. Basing on whole genome sequencing (WGS), we characterized the&nbsp;<em>E. coli</em>&nbsp;strain E706, which harbors a series of virulence and resistance genes, CRISPR candidate elements, prophage related sequences, as well as genomic islands. The plasmid pLKJULY7989 in E706 is a chimera plasmid made up of a basic IncFIB plasmid backbone with class 1 integron and multi-resistance genes. pLKJULY7989 carries a class 1 integron with the existence of gene cassette&nbsp;<em>dfrA12</em>-<em>aadA2</em>&nbsp;and class 1 integrase gene&nbsp;<em>intl1</em>, which is lacked in homologous plasmid pEHS30-1. The class 1 integron was detected only harboring a class 1 integrase gene, and gene cassette&nbsp;<em>dfrA12</em>-<em>aadA2</em>. The complete sequence we reported here will provide valuable information for a more understanding about the genomic structure and pathogenic characteristics of the genome of&nbsp;<em>E. coli</em>.</p> Escherichia coli, plasmid, whole genome sequencing, resistance gene Pakistan Agricultural Scientists Forum https://thejaps.org.pk/AbstractView.aspx?mid=Biot-19-0046