17 Alfred Maroyi Journal of Animal and Plant Sciences JAPS 20252025/06/26 35 3 625-637 1018-7081 https://doi.org/10.36899/JAPS.2025.3.0053 <p><em>Turraea floribunda</em>&nbsp;Hochst. is a small to medium-sized tree used as traditional medicine in tropical Africa. This study was aimed at providing a comprehensive review of the ethnobotanical uses, phytochemistry and pharmacological properties of&nbsp;<em>T. floribunda</em>. This information was collected from several online databases such as PubMed&reg;, Web of Science, ScienceDirect&reg;, Google Scholar, SpringerLink&reg;, Scopus&reg; and SciELO and pre-electronic literature sources such as books, book chapters and scientific publications obtained from the university library. This study showed that&nbsp;<em>T. floribunda</em>&nbsp;is used as traditional medicine in 53.8% of the countries where the species is indigenous. The traditional medicines prepared from the bark, leaves, roots and stem bark of&nbsp;<em>T. floribunda&nbsp;</em>are used to treat and manage 20 human and livestock diseases and ailments in central, eastern and southern Africa. The phytochemical evaluation of the species revealed that it contains diterpenoids, alkanes, sesquiterpenoids, methyl esters, triterpenoids, fatty acids, esters, fatty alcohols, limonoids, sterols and hydrocarbons. Ethnopharmacological research showed that the crude extracts and phytochemical compounds isolated from&nbsp;<em>T. floribunda</em>&nbsp;have antibacterial, antifungal, anti-hypertensive, anti-inflammatory, antioxidant, antiplasmodial, antiprotozoal, cytotoxicity, insecticidal and larvicidal activities. Detailed studies focusing on toxicological evaluations,&nbsp;<em>in vivo</em>&nbsp;and clinical research aimed at corroborating the traditional medical applications of&nbsp;<em>T. floribunda&nbsp;</em>are recommended.</p> Mahogany, Meliaceae, traditional medicine, tropical Africa, Turraea floribunda. Pakistan Agricultural Scientists Forum https://thejaps.org.pk/AbstractView.aspx?mid=2024-JAPS-2103