17 S. M. Jazayeri L. C. García Cruzatty R. Villamar-Torres Journal of Animal and Plant Sciences JAPS 20192019/04/01 29 2 539-548 1018-7081 NA <p><em>Arabidopsis</em>&nbsp;is the ever most well-known plant model. Publishing genome of&nbsp;<em>A. thaliana</em>&nbsp;has restructured biological sciences towards more knowledge on multi and interdisciplinary researches based on genomic data. Eleven approved species of&nbsp;<em>Arabidopsis</em>&nbsp;were classified into 4 groups. Despite of its importance in biology, only three&nbsp;<em>Arabidopsis&nbsp;</em>species genomes are available. Genomes, proteins and gene models in three&nbsp;<em>Arabidopsis</em>&nbsp;species including&nbsp;<em>A. halleri, A. lyrata</em>&nbsp;and&nbsp;<em>A. thaliana</em>&nbsp;were compared. Genomic comparison disclosed 80-90 % of similarity for proteins and gene models among three species. The clustered protein sets showed 79% of common orthologue proteins among three species. Transcript pairwise comparisons among three species showed a similarity range of 82-92%. Twenty-six species-specific clustered proteins related to heavy metal response are highlighted in&nbsp;<em>A. halleri</em>. They function in transport, phytochelat, protein degradation, cell wall formation, detoxification and signaling.</p> Arabidopsis, genes, genomic comparison, heavy metal, tolerance Pakistan Agricultural Scientists Forum https://thejaps.org.pk/AbstractView.aspx?mid=2019-JAPS-225