17 M. Kamran M. U. D. Ahmad A. A. Anjum A. Maqbool K. Muhammad M. Nawaz N.U. Hudda S. Sana M. A. Ali Journal of Animal and Plant Sciences JAPS 20142014/10/01 24 5 1565-1568 1018-7081 NA <p><em>Antibiotic susceptibility pattern</em><em>of</em><em>&nbsp;Pasteurella multocida&nbsp;</em><em>causing&nbsp;</em>hemorrhagic septicemia in buffaloes was determined. The&nbsp;<em>Pasteurella multocida&nbsp;</em><em>(n=11) were isolated&nbsp;</em>from healthy (04) and diseased buffaloes (07) of four districts of Sargodha division. Isolates were identified by cultural,&nbsp;<em>biochemical and serological characteristics, and confirmed by specie specific polymerase chain reaction.</em>&nbsp;All i<em>solates were subjected to antibiotic susceptibility testing against&nbsp;</em>gentamicin, erythromycin, amoxicillin, ampicillin, chloramphenicol, ciprofloxacin, norfloxacin, enrofloxacin, sulfadiazine and amikacin by disc diffusion method. Results revealed that&nbsp;<em>P. multocida</em>&nbsp;were highly sensitive to enrofloxacin (90.91 %) followed by gentamicin, chloramphenicol, ciprofloxacin and norfloxacin (72.73%). Susceptibility of&nbsp;<em>P. multocida</em>&nbsp;isolates was low against ampicillin and amoxicillin (45.45%), amikacin (36.36%), sulfadiazine (18.18%) and erythromycin (18.18%). It was concluded that quinolones (enrofloxacin, ciprofloxacin and norfloxacin) are better choice for the treatment of hemorrhagic septicemia as the level of resistance in&nbsp;<em>P. multocida</em> against the macrolides, sulfa drugs and beta lactams has increased enormously.</p> Hemorrhagic septicemia, Pasteurella multocida, Buffalo, Antibiotic susceptibility, Quinolones Pakistan Agricultural Scientists Forum https://thejaps.org.pk/AbstractView.aspx?mid=2014-JAPS-222