17 S. Zhuang R. Yan W.C. Dong T. Zhang G.J. Chang X. Z. Shen Journal of Animal and Plant Sciences JAPS 20142014/02/01 24 1 135-141 1018-7081 NA <p>The aim of this study was to investigate the effects of different levels of forage and concentrates diets on the metabolism of glucose, &beta;-hydroxybutyrate (BOHB) and nonesterified fatty acid (NEFA) in livers of nonlactating goats. Six catheterized GuanZhong goats (40&plusmn;2 kg weight) were fed high concentrate diet (HC, 40% hay, 60% concentrate) or high forage diets (HF, 60% hay, 40% concentrate). Blood samples were simultaneously taken from the portal, hepatic and arterial catheters at 0 h, before feeding, 2, 4, 6 and 8 h after feeding. The HC fed goats exhibited higher (P&lt;0.01) plasma glucose concentration and arterial flow accompanied by NEFA, BOHB(P&lt;0.01) and hepatic glucagons concentrations (P&lt;0.10) while NEFA portal flow and BOHB hepatic flow decreased (P&lt;0.05). Glucose portal-arterial concentration difference and hepatic-portal concentration differences in BOHB and NEFA tended to decreased (P&lt;0.10) with increasing NEFA portal and hepatic arterial concentration differences (P&lt;0.05) in HC fed goats. There were no differences in net flow of glucose, BOHB and NEFA across splanchnic tissues, but a decreased net portal absorption in NEFA (P&lt;0.05) accompanied with a tendency for depressing its net PDV plus hepatic uptake (P&lt;0.10). In conclusion, the high concentrates diet may increase hepatic gluconeogenesis in nonlactating goats.</p> Concentrate, Liver, Glucose, Nonesterified fatty acid, β-Hydroxybutyrate, Goat Pakistan Agricultural Scientists Forum https://thejaps.org.pk/AbstractView.aspx?mid=2014-JAPS-20