[{
  "type": "article-journal",
  "title": "EFFECT OF IBUPROFEN ALONE AND INCONJUGATION WITH VITAMIN E AND SELENIUM ON EXPERIMENTALLY INDUCED COCCIDIOSIS IN BROLIERS",
  "author": [
    {
      "family": "M.A",
      "given": ""
    },
    {
      "family": "Sattar",
      "given": ""
    },
    {
      "family": "Ashraf",
      "given": ""
    },
    {
      "family": "Mehdi",
      "given": ""
    },
    {
      "family": "Rafique",
      "given": ""
    },
    {
      "family": "Mahmood",
      "given": ""
    },
    {
      "family": "Aslam",
      "given": ""
    },
    {
      "family": "Hussain",
      "given": ""
    },
    {
      "family": "Zia",
      "given": ""
    }
  ],
  "issued": {
    "date-parts": [[2020]]
  },
  "container-title": "Journal of Animal and Plant Sciences",
  "ISSN": "1018-7081",
  "volume": "30",
  "issue": "3",
  "page": "627-633",
  "DOI": "https://doi.org/10.36899/JAPS.2020.3.0074",
  "abstract": "<p>The aim of study was to determine the effect of (Brufen<sup>TM</sup>) alone and in conjugation with vitamin E and Selenium in broilers against coccidiosis. One hundred randomly allocated (25 birds in each group&nbsp;<em>i.e.</em>, A, B, C &amp; D) day-old broiler chicks underwent the current trial. Group A, B and C were challenged with 60,000-70,000 sporulated oocysts of genus&nbsp;<em>Eimeria&nbsp;</em>at 21<sup>st</sup>&nbsp;day of age. Group A and B were administered with (Brufen<sup>TM</sup>) and combination of (Brufen<sup>TM</sup>) with vitamin E and Selenium (E-Sel<sup>TM</sup>) @ 100mg/kg body weight and 1ml/10 liters of drinking water, respectively. Group C and D were kept as negative (infected &amp; un-medicated) and positive (un-infected &amp; un-medicated) controls, respectively. Therapeutic response was measured on the basis of mortality, oocysts count, weight gains, coccidial lesion scorings and weight of lymphoid organs. Maximum mortality was observed in group C (17/25), followed by group A (12/25), than in group B (8/25) post coccidial infection. Coccidial lesion scores and oocysts count were significantly lower in groups (A &amp; B) administered with Ibuprofen. Moreover, maximum weight gain and reduced lymphoid organ to body weight ratio were also observed in chicken of group B as compared to A, C and D. The study suggested synergistic and enhanced protective response of Ibuprofen in combination with vitamin E and Selenium against chicken coccidiosis.</p>",
  "publisher": "Pakistan Agricultural Scientists Forum",
  "URL": "https://thejaps.org.pk/AbstractView.aspx?mid=VS-17-0087"
}]