[{
  "type": "article-journal",
  "title": "BIOLOGICAL SCREENING OF CRUDE EXTRACT OF PENICILLIUM SP. EU0013",
  "author": [
    {
      "family": "Kalsoom",
      "given": ""
    },
    {
      "family": "Shah",
      "given": ""
    },
    {
      "family": "Iqbal",
      "given": ""
    }
  ],
  "issued": {
    "date-parts": [[2017]]
  },
  "container-title": "Journal of Animal and Plant Sciences",
  "ISSN": "1018-7081",
  "volume": "27",
  "issue": "4",
  "page": "1209-1216",
  "DOI": "NA",
  "abstract": "<p>Medicinal plants and microbe are a rich source of secondary metabolites. The aim of the current work was to isolate the crude extract from&nbsp;<em>Penicillium&nbsp;</em>sp. EU0013 and study its antimicrobial potential at Natural Products Laboratory, The University of Agriculture Peshawar. Fermentation of&nbsp;<em>Penicillium</em>&nbsp;EU0013 was carried out using potato dextrose broth. The yield of crude ethyl acetate extract was calculated 1gmL-1 from static flask fermentation. The fungal extract was screened for bench-top bioassays including antifungal, antibacterial, phytotoxic, insecticidal and nematicidal activities. Results showed that at 100, 200 and 300 &micro;g.mL-1 the extract exhibit antibacterial activity ranging from 13.4 to 80.7mm against&nbsp;<em>E. coli</em>,&nbsp;<em>Bacillus subtilis</em>, &nbsp;<em>Xanthamonas</em>&nbsp;sp. and&nbsp;<em>Proteus vulgaris</em>, and 14.3 to 80.7 mm against&nbsp;<em>Aspergillus flavus</em>,&nbsp;<em>Alternaria alternata</em>,&nbsp;<em>A. niger</em>&nbsp;and&nbsp;<em>Fusarium oxyspourm</em>. The phytotoxic, insecticidal and nematicidal activity on 7thday, 24 hour and again 7 days of&nbsp;<em>Penicillium</em> extract increased with increased of dose with highest mortality of 16.6, 63.32 and 85.75 % at 200, 200 and 100 &mu;g. mL-1 respectively.</p>",
  "publisher": "Pakistan Agricultural Scientists Forum",
  "URL": "https://thejaps.org.pk/AbstractView.aspx?mid=2017-JAPS-153"
}]