[{
  "type": "article-journal",
  "title": "EFFECT OF MIKANIA CORDATA ON NON-SPECIFIC IMMUNE RESPONSE AND SURVIVAL OF LABEO ROHITA AGAINST APHANOMYCES INVADANS",
  "author": [
    {
      "family": "Kumar",
      "given": ""
    },
    {
      "family": "Roy",
      "given": ""
    },
    {
      "family": "Barman",
      "given": ""
    }
  ],
  "issued": {
    "date-parts": [[2016]]
  },
  "container-title": "Journal of Animal and Plant Sciences",
  "ISSN": "1018-7081",
  "volume": "26",
  "issue": "6",
  "page": "1833-1842",
  "DOI": "NA",
  "abstract": "<p>The study was conducted to evaluate the efficacy of&nbsp;<em>Mikania cordata</em>&nbsp;leaf powder on non-specific immune response and disease resistance of&nbsp;<em>Labeo rohita</em>&nbsp;fingerlings against the&nbsp;<em>Aphanomyces invadans&nbsp;</em>infection.&nbsp;<em>M. cordata&nbsp;</em>extract was incorporated in the diets (at 0.0%, 1%, 2% and 3%) of&nbsp;<em>L. rohita</em>&nbsp;fingerlings (19&plusmn;0.95g). Blood and serum sampling was carried out on 0th day, 14th day, 28th day and 42th day of feeding trials to determine NBT levels, myeloperoxidase activity, phagocytic activity and serum lysozyme activity, as compared to the control group. Fish were challenged with&nbsp;<em>Aphanomyces invadans&nbsp;</em>after 42 days and mortalities were recorded over 18 days post infection. The results revealed that fishes fed with&nbsp;<em>Mikania cordata&nbsp;</em>extract showed significant (p&lt;0.05) increase in NBT levels, myeloperoxidase activity, phagocytic activity and serum lysozyme activity when compared to the control group. Dietary&nbsp;<em>M. cordata&nbsp;</em>extract of 2% showed significantly (<em>p</em><em>&lt;</em>0.05) higher protection relative percentage survival (RPS 71.06&plusmn; 5.773%) from&nbsp;<em>A. invadans&nbsp;</em>infection than control. These results indicate that&nbsp;<em>M. cordata</em>&nbsp;leaf powder stimulates the non-specific immunity and makes&nbsp;<em>L. rohita</em>&nbsp;more resistant to fungal infection (<em>A. invadans</em>).</p>",
  "publisher": "Pakistan Agricultural Scientists Forum",
  "URL": "https://thejaps.org.pk/AbstractView.aspx?mid=2016-JAPS-240"
}]