[{
  "type": "article-journal",
  "title": "EFFECT OF DIETARY SUPPLEMENTATION OF ACETONE EXTRACTS OF NIGELLA SATIVA L. SEEDS ON SERUM CHOLESTEROL AND PATHOGENIC INTESTINAL BACTERIAL COUNT IN BROILERS",
  "author": [
    {
      "family": "Siddiqui",
      "given": ""
    },
    {
      "family": "Islam",
      "given": ""
    },
    {
      "family": "Sayed",
      "given": ""
    },
    {
      "family": "Hossain",
      "given": ""
    }
  ],
  "issued": {
    "date-parts": [[2015]]
  },
  "container-title": "Journal of Animal and Plant Sciences",
  "ISSN": "1018-7081",
  "volume": "25",
  "issue": "2",
  "page": "372-379",
  "DOI": "NA",
  "abstract": "<p>This study aimed to investigate effects of varying doses of&nbsp;<em>Nigella sativa</em>&nbsp;seed powder or acetone extracts in diet on feed intake, mortality, serum lipid profiles and population of intestinal microflora of broilers. A total 168, day-old broiler chicks (Cobb 500) were&nbsp;&nbsp;<em>ad-libitium</em>&nbsp;manually prepared feeds supplemented with 0, 1.5, 2.5, 3.0% seed powder or &nbsp;0, 0.2, 0.4% acetone extracts of&nbsp;<em>N. sativa</em>&nbsp;seed for 4 weeks. The experiment was conducted in a complete randomized design (CRD) with seven treatments and three replications.&nbsp;<em>N. sativa</em>&nbsp;supplemented feed had no significant effects on feed intake, body weight and mortality rate of broiler. However, supplementation of either 3.0% seed powder or 0.4% extracts of&nbsp;<em>N. sativa&nbsp;</em>seeds significantly (p&lt;0.05) decreased serum cholesterol and triglycerides contents in broiler. Furthermore, both&nbsp;<em>N. sativa</em>&nbsp;seed powder and extract supplemented feed also suppressed harmful bacterial (<em>Escherichia coli</em>) population in the feces. These results suggest that&nbsp;<em>N. sativa</em> seed might have potential as an alternative to hazardous synthetic feed additives (antibiotics) to formulate low cost and environment-friendly diet for the broiler.</p>",
  "publisher": "Pakistan Agricultural Scientists Forum",
  "URL": "https://thejaps.org.pk/AbstractView.aspx?mid=2015-JAPS-53"
}]