[{
  "type": "article-journal",
  "title": "PROTECTIVE EFFECTS OF γ -AMINOBUTYRIC ACID (GABA) ON THE SMALL INTESTINAL MUCOSA IN HEAT-STRESSED WENCHANG CHICKEN",
  "author": [
    {
      "family": "Chen",
      "given": ""
    },
    {
      "family": "Xie",
      "given": ""
    },
    {
      "family": "Y.Hu",
      "given": ""
    },
    {
      "family": "Tang",
      "given": ""
    },
    {
      "family": "Shao",
      "given": ""
    },
    {
      "family": "Li",
      "given": ""
    }
  ],
  "issued": {
    "date-parts": [[2015]]
  },
  "container-title": "Journal of Animal and Plant Sciences",
  "ISSN": "1018-7081",
  "volume": "25",
  "issue": "1",
  "page": "78-87",
  "DOI": "NA",
  "abstract": "<p>We explored the effects of heat stress (HS) and &gamma;-aminobutyric acid (GABA) treatment on the structure and development of small intestinal mucosa in Wenchang chicken. One-day old male Wenchang chickens were randomly divided into control group (CK), heat stress group (HS) and GABA+HS group. The chickens from GABA+HS group were fed with 0.2 ml 0.5% GABA solution daily. In addition, the chicken from HS and GABA+HS groups were subjected to heat stress treatment at 40 &plusmn;0.5&deg;C for 2h during 13:00-15:00 every day. Results showed that compared with CK group, HS group exhibited marked&nbsp;<a id=\"OLE_LINK13\" name=\"OLE_LINK13\"></a><a id=\"OLE_LINK12\" name=\"OLE_LINK12\"></a>decline&nbsp;in villus length, mucosa thickness, intestinal wall thickness, and crypt depth in duodenum and ileum, and significantly fewer goblet cells (<em>P&lt;0.05</em>). In contrast, compared with HS group, GABA+HS group exhibited enhanced villus length, mucosa thickness, intestinal wall thickness, and crypt depth in duodenum and ileum, as well as a much higher number of goblet cells (<em>P&lt;0.05</em>). Therefore, heat stress caused significant structural damages to chicken small intestinal mucosa, and markedly reduced the number of goblet cells. GABA showed protective effects to alleviate HS-induced damages of the intestinal mucosa and increased the number of goblet cells.</p>",
  "publisher": "Pakistan Agricultural Scientists Forum",
  "URL": "https://thejaps.org.pk/AbstractView.aspx?mid=2015-JAPS-12"
}]