[{
  "type": "article-journal",
  "title": "ANTI-HEMOLYTIC PROPERTY OF LOCAL MEDICINAL PLANT(S) UPON PAKISTANI COBRA VENOMINDUCED HEMOLYSIS",
  "author": [
    {
      "family": "Asad",
      "given": ""
    },
    {
      "family": "Sabih",
      "given": ""
    },
    {
      "family": "Chaudhory",
      "given": ""
    },
    {
      "family": "Ahmad",
      "given": ""
    },
    {
      "family": "Hussain",
      "given": ""
    },
    {
      "family": "Izhar",
      "given": ""
    },
    {
      "family": "Akmal",
      "given": ""
    },
    {
      "family": "Shahzad",
      "given": ""
    },
    {
      "family": "Hussain",
      "given": ""
    }
  ],
  "issued": {
    "date-parts": [[2014]]
  },
  "container-title": "Journal of Animal and Plant Sciences",
  "ISSN": "1018-7081",
  "volume": "24",
  "issue": "6",
  "page": "1701-1708",
  "DOI": "NA",
  "abstract": "<p>Present study was carried out to assess scientifically anti-hemolytic properties of medicinal plants against Pakistani cobra induced hemolysis. Venom from<em>&nbsp;Naja naja</em>&nbsp;and&nbsp;<em>Naja naja karachiensis</em>&nbsp;were found to destabilize human red blood corpuscles membrane (HRBC) however, the effect of later was &nbsp;found somewhat severe. Against&nbsp;<em>Naja naja karachiensis</em>&nbsp;venom twenty six medicinal plants of Pakistan were evaluated but only&nbsp;<em>Cedrus deodara</em>&nbsp;G. Don (P˃0.5) was proved the most effective (72%) in stabilizing HRBC membranes.&nbsp;<em>Althaea officinalis</em>&nbsp;Linn<em>, Calotropis procera</em>&nbsp;(Wild.) R.Br,&nbsp;<em>Citrus limon&nbsp;</em>(L)<em>.&nbsp;</em>Burm. f<em>,</em>&nbsp;<em>Enicostemma hyssopifolium</em>&nbsp;(Willd.) Verdoorn,&nbsp;<em>Leucas capitata</em>&nbsp;Desf and&nbsp;<em>Stenolobium stans</em>&nbsp;(L) D. Don were found anti-hemolytic (0.5˃P˃0.1) at various concentration range (20 to 320 &micro;g/mL) in comparison with standard anti-sera (56%). Flowers extract of&nbsp;<em>Calotropis procera</em>&nbsp;(Wild.) R.Br and bulbs of&nbsp;<em>Allium cepa</em>&nbsp;L were found helpful to neutralize snake venom hemolysis at P˂0.1. However, remaining plants extract (p<em>˂0.05</em>) were found to be hemolytic and potentiated the effect of venom instead of having anti-hemolytic potentials. On scientific basis this study emphasizes to rationalize, the use of listed medicinal plants in traditional system of medicine as an anti-hemolytic. Nevertheless, further study is inevitable to identify and isolate bio-active compound(s) from above cited potential medicinal plant(s) extract.</p>",
  "publisher": "Pakistan Agricultural Scientists Forum",
  "URL": "https://thejaps.org.pk/AbstractView.aspx?mid=2014-JAPS-244"
}]