tent for New Div Tag Goes Here
EFFECT OF IBUPROFEN ALONE AND INCONJUGATION WITH VITAMIN E AND SELENIUM ON EXPERIMENTALLY INDUCED COCCIDIOSIS IN BROLIERS
Hafeez. M.A*1, A. Sattar2, K. Ashraf1, M. Mehdi1, A. Rafique3, M.S. Mahmood4, F. Aslam5, I. Hussain5 and M.R. Zia4
1Department of Parasitology, University of Veterinary and Animal Sciences, Lahore, Pakistan
2Department of Pharmacology and Toxicology, University of Veterinary and Animal Sciences, Lahore, Pakistan
3Department of Zoology, GC University Faisalabad, Pakistan
4Institute of Microbiology, University of Agriculture, Faisalabad, Pakistan
5Livestock and Dairy Development Department, Punjab
Corresponding author’s email: abdul.hafeez@uvas.edu.pk
ABSTRACT
The aim of study was to determine the effect of (BrufenTM) alone and in conjugation with vitamin E and Selenium in broilers against coccidiosis. One hundred randomly allocated (25 birds in each group i.e., A, B, C & D) day-old broiler chicks underwent the current trial. Group A, B and C were challenged with 60,000-70,000 sporulated oocysts of genus Eimeria at 21st day of age. Group A and B were administered with (BrufenTM) and combination of (BrufenTM) with vitamin E and Selenium (E-SelTM) @ 100mg/kg body weight and 1ml/10 liters of drinking water, respectively. Group C and D were kept as negative (infected & un-medicated) and positive (un-infected & un-medicated) controls, respectively. Therapeutic response was measured on the basis of mortality, oocysts count, weight gains, coccidial lesion scorings and weight of lymphoid organs. Maximum mortality was observed in group C (17/25), followed by group A (12/25), than
in group B (8/25) post coccidial infection. Coccidial lesion scores and oocysts count were significantly lower in groups (A & B) administered with Ibuprofen. Moreover, maximum weight gain and reduced lymphoid organ to body weight ratio were also observed in chicken of group B as compared to A, C and D. The study suggested synergistic and enhanced protective response of Ibuprofen in combination with vitamin E and Selenium against chicken coccidiosis.
Key words: coccidiosis, ibuprofen, vitamin E and selenium, broilers,
|