EVALUATION OF ANTI-INFLAMMATORY AND ANALGESIC POTENTIAL OF AQUEOUS METHANOLIC EXTRACT OF THUJA ORIENTALIS IN ALBINO RATS
M. Z. Tanveer1, A. Javeed1†, M. Ashraf1, M. U. Rehman2 and S. M. M. Anjum3
1Department of Pharmacology & Toxicology, University of Veterinary and Animal Sciences, Lahore - Pakistan
2Department of Pathology, University of Veterinary and Animal Sciences, Lahore –Pakistan
3Institute of Pharmaceutical Sciences, University of Veterinary and Animal Sciences, Lahore –Pakistan
†Correspondence author’s email: firstname.lastname@example.org
This study was conducted for evaluating a natural source to treat inflammation and pain, to avoid the severe side effects of currently used agents for these ailments. Thuja Orientalis (More Pankh) is commonly used for the treatment of pain and inflammatory disorders in traditional medicine. Carrageenan induced inflammatory model, acetic acid induced writhing test and hot plate methods were used to evaluate anti-inflammatory, peripheral and central analgesic properties of aqueous methanolic extract of Thuja Orientalis fruit (To-Cr) in albino rats. Completely randomized design (CRD) was constructed for the study and one way ANOVA was applied to compare means. The results showed that TO-Cr has significant anti-inflammatory and analgesic properties.
Key words: Analgesic, inflammation, oedema, anti-inflammatory, carrageenan, Thuja Orientalis