The effect of dietary supplementation of alpha-tocopherol, L-carnitine and ginger on blood biochemical profile of Hubbard and Cobb under the summer season was evaluated. A total of three hundred and twenty broiler chicks (both strains) were divided into two groups and four subgroups. In each strain subgroup, one was kept as control while other sub groups were provided with alpha-tocopherol, ginger and L-carnitine in basal diets until sixth week. Average temperature and humidity were 31.89 °C and 58.26% respectively. Supplementation of the diet with L-carnitine, ginger and alpha-tocopherol significantly (P<0.01) decreased mean serum cholesterol, ALT, glucose, triglyceride, LDL and increased HDL serum protein. The results of alpha-tocopherol were comparatively better than the other two additives. It is concluded that supplementation of diets with ginger, alpha-tocopherol and L-carnitine improve broiler blood biochemical parameters. The blood biochemical parameters did not vary between the broiler strains.