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Volume 22, No. (3), 2012 (September)
TOXIC EFFECTS OF SCORPION, HEMISCORPIUS LEPTURUS (HEMISCORPIIDAE) VENOM ON MICE
R. Dehghani, T. Khamehchian, B. Vazirianzadeh H. Vatandoost, S. A. Moravvej

R. Dehghani, T. Khamehchian, B. Vazirianzadeh H. Vatandoost, S. A. Moravvej
1 Department of Environmental Health, Kashan University of Medical Sciences, Kashan, Iran
2 Department of Medical Entomology, School of Health, and Infectious and Tropical Diseases Research Centre, Ahvaz
3 Jundishapur University of Medical Sciences, Ahvaz, Iran
4 Department of Medical Entomology and Vector Control, School of Public Health and National Institute of Health
5 Research, Tehran University of Medical Sciences, Tehran, Iran
Corresponding Author: babakvazir@yahoo.co.uk
DOI: NA
Page Number(s): 593-596
Published Online First: June 01, 2012
Publication Date: June 01, 2012
ABSTRACT

Scorpion stings are common in Iran, particularly in the southern and southwest regions of the country, and they pose a serious health problem. Hemiscorpius lepturus is the most venomous scorpion in the region. The present study was conducted to investigate the in vivo effects of scorpion venom in experimental mice. Haematological parameters (white and red blood cells numbers and haematocrit levels) and histological changes (skin, stomach, spleen, heart, liver, kidney, lung, pancreas, small intestine, anal, adrenal, brain, and bladder) venom were measured in mice. The results revealed that H. lepturus species has negative effects on both local and systemic tissues in mice, which may include damage to the skin and internal organs, respectively.
Keywords: Hemiscorpius lepturus, venom, mice, in vivo, haematological studies, histological studies
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Electronic ISSN: 2309-8694

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